Methylfolate 1000 mcg | 60 Quick Melt Tablets

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Folate + B12

Quatrefolic is the metabolically active and coenzymated form of folate. The body cannot make folate on its own and must obtain for it from foods or dietary supplement. However, folic acid and also food folate are not biologically active and need to be converted to the metabolically active 5-MTHF. Research has shown that Quatrefolic results in a 3.1 times higher blood folate concentration of 5-MTHF than regular folic acid. Supports immunity, cardiovascular, neurological, and cognitive health. Helps to support normal early fetal development including the brain and spinal cord, and reduce the risk of neural tube defects when taken daily at least three months prior to becoming pregnant and during early pregnancy. Helps prevent folate deficiency, produce red blood cells and is a factor in the maintenance of good health.

What Does Coenzymated Mean?

In order for B vitamins to utilized effectively by the body, they must be converted into their metabolically active coenzyme forms. For example, the coenzyme form of folate is 5-methyltetrahydrofolate (5-MTHF). A coenzyme is a naturally occurring compound that partners with specific enzymes in order to help promote a number of beneficial metabolic reactions in the body. Without the coenzyme, the enzyme cannot promote the biochemical reaction that is responsible for our survival. This dual cooperation between coenzyme and enzyme is a process called coenzymated.

Taking B vitamins already in their coenzymated forms allows the body to use them directly. Thus, the amount that is needed by the body is less in order to achieve the same benefits. Biocoenzymated takes it one step further. Using proprietary EnviroSimplex technology, Natural Factors has created a unique biocoenzymated processing using organic, farm fresh plant extract from whole food sources and the coenzyme form of B vitamins. The synergy between the phytochemicals found in these plant extracts and the coenzyme B vitamin optimizes absorption.

The results? Biocoenzymated delivers the most metabolically active nutrients to your cells to utilize most effectively.

Feel the difference!


  • Keep out of reach of children.

Suggested Use:

Chew or dissolve 1 tablet per day in the mouth before swallowing or as directed by a health professional.

Supplement Facts:

Serving Size: 1 Tablet
  Per Serving: %DV:
Folate (from (6S) – 5 -methyltetrahydrofolate
acid (MTHF), glucosamine salt, Quatrefolic)
1,700 mcg DFE (1000 mg folic acid) 425%
B12 (methylcobalamin) 50 mcg 2,083%

Other Ingredients: Lactose, microcrystalline cellulose, croscarmellose sodium, Farm Fresh Factors†, magnesium stearate (vegetable

†Active Vegetables – Organic kale, organic alfalfa, organic cilantro leaf, organic parsley, caperberry, sprouted garlic, organic artichoke, organic black radish,
organic dandelion, barley grass, pepper, organic celery seed, organic beetroot, organic tomato;

Cruciferous Vegetables – A broad spectrum of full active
glucosinolates and myrosinase enzymes from wasabi rhizome (Wasabia japonica) and fresh freeze-dried sprouted broccoli, organic upland cress, daikon, red radish, organic
cauliflower, organic cabbage, organic arugula, organic watercress leaf;

Ultra Fruit Polyphenols – Grape, pomegranate, strawberry, organic blueberry, raspberry,
bilberry, organic indian gooseberry, schizandra berry, red orange, organic acai berry;

Herbals and Plants – Theracurmin curcumin, organic decaffeinated green tea
extract, organic ginger rhizome, organic echinacea, organic oregano, organic peppermint, organic spearmint;

Whole Plant Sea Vegetables – Organic spirulina, organic
chlorella, red algae, blue green algae, kelp.

Allergen information:

  • Contains milk.
  • Contains no artificial colors, preservatives, or sweeteners; no starch, wheat, gluten,
    yeast, soy, corn, egg, fish, shellfish, salt, tree nuts, or GMOs. 
  • Suitable for vegetarians.