Excellent Transdermal Absorption
ClearPatch Progesterone USP 1.5% Lotion is a transdermal preparation containing 15 mg/ml of progesterone (0.5 mg per average drop). Progesterone is fully dissolved and easily absorbable.
Dosage: An appropriate dose is the minimal amount that alleviates hormonal imbalance symptoms. The following suggested doses are intended to restore physiological level of progesterone, therefore restoring its balance in relation to estrogen. ClearPatch Progesterone 1.5% Lotion can be applied once (in the morning) or twice a day (in the morning and before retiring). In most cases it is better to use twice a day. If the late evening application causes undesired increase of energy, apply the lotion no later than 4 hours before bedtime.
Dr. John R. Lee and other authors recommend using progesterone for:
Menopause or postmenopause: 5–20 drops once or twice daily for 21 days; discontinue for 7 days and repeat. If discontinuation causes difficult to tolerate reoccurrence of symptoms, the break can be shortened to 3 days. The break is necessary to maintain the sensitivity of progesterone receptors, as well as to prevent its possible buildup in the body. If you have never used progesterone and do not know how much your body requires for balance, start using 5 drops twice daily. Increase the dose gradually until symptoms subside or disappear. Do not exceed 40 drops per day without consulting your doctor. After 1-2 months try decreasing the number of drops to find the correct dose for your body. Use the smallest dose at which symptoms don’t reoccur.
Women who do not menstruate can also use an easier to remember alternative application schedule: use the lotion for 25 days of the calendar month and discontinue for the rest of the month.
Premenopause or PMS: Start using in the middle of your cycle between the 10th and 12th day depending on the cycle’s length. First day of cycle is the first day of menstruation. Use 2-10 drops once or twice daily for 14 days. When irregular cycles cause earlier menstruation, discontinue using until the middle of next cycle. According to Dr. Lee, cycles should become normalized after 2-3 months of usage. Insufficient progesterone level in the body causes reduced sensitivity of estrogen receptors. Initial progesterone supplementation restores their sensitivity, which may cause some women to experience certain symptoms related to estrogen dominance: water retention, headache and enlarged breasts. It is important to remember that these symptoms will disappear in two weeks to two months. To avoid the symptoms we recommend starting with a lower dose, gradually increasing it until the desired dose is reached.
Dr. Lee recommends progesterone for prevention of osteoporosis:
Follow one of the above schedules, apply twice a day. Keep in mind that slim, small, older women usually need less progesterone than younger women with greater body weight and that even a minimal dose is beneficial.
Men: Average daily dose is 4 – 8 drops. Do not exceed 6 drops per day without consulting your heath care professional. Use for 3 consecutive weeks, discontinue for 1 week and repeat. Alternatively, use for 25 days in a month, discontinue for the rest of the month and repeat the cycle.
How and where to apply: Invert bottle holding it vertically for proper drop delivery. Gently massage to thin skin areas: palms, inner arms, chest, neck or backside of the knees. It is best to alternate between application sites. Apply to clean skin only. Do not apply other lotions or creams to the area of ClearPatch application – they can reduce progesterone absorption.
When to expect results?
Improvement can be noticed after a few days of progesterone supplementation, depending on symptoms. In case of substantial progesterone deficiency, a few weeks might be necessary for the symptoms to subside.
How long to use natural progesterone?
As long as you need its benefits. If you are using hormone replacement therapy (HRT) and want to switch to health-promoting natural progesterone, Dr. Lee recommends complete discontinuation of synthetic progestins if your therapy includes them, and reducing estrogen dose by half then gradually taper off if possible. Many women can discontinue using estrogens after several months of natural progesterone supplementation. For more information refer to the books suggested below.
- Do not use progesterone while using hormone-based birth control.
- Consult a doctor in case of a serious health condition, taking prescription medication, when using hormonal therapy, pregnant, planning to become pregnant or nursing.